The World Health Organization (WHO) recommends routine immunization in all countries where the disease is common. This should typically occur between nine and twelve months of age. Those travelling to areas where the disease occurs should also be immunized. Additional doses after the first are generally not needed.
Yellow fever vaccine is generally safe. This includes in those with HIV infection but without symptoms. Mild side effects may include headache, muscle pains, pain at the injection site, fever, and rash. Severe allergies occur in about eight per million doses, serious neurological problems occur in about four per million doses, and organ failure occurs in about three per million doses.
It is likely safe in pregnancy and therefore recommended among those who will be potentially exposed. It should not be given to those with very poor immune function. Yellow fever vaccine came into use in 1938.It is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system.
The vaccine is made from weakened yellow fever virus. Some countries require a yellow fever vaccination certificate before entry from a country where the disease is common.